产品编号
1032295
CAS 号
41443-28-1
中文名称
ODQ
MDL 号
MFCD00792620
分子量
187.15
存储条件
2-8°C
网页展示纯度为入库指导纯度值，各批次间存在一定差异，实际纯度以收货为准
熔点
160-170 °C
沸点
321.89 °C at 760 mmHg
闪点
旋光
描述
TPSA
60.4
LogP
0.8357
H_Acceptors
5
H_Donors
0
Rotatable_Bonds
0
[1]. Ronald Fiscus, et al. ODQ, an inhibitor of soluble guanylyl cyclase (nitric oxide-activated enzyme), enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells. Cancer Res May 1 2007 (67) (9 Supplement) LB-43.
[2]. Zacharowski K, et al. The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock. Crit Care Med. 2001;29(8):1599-1608.
[3]. Carmen G León-Paravic, et al. Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels. J Biol Chem. 2014 Dec 26;289(52):36150-7.
[4]. Changlong An, et al. Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension. PLoS One. 2015 Aug 10;10(8):e0134876.
[5]. Cinzia Fionda, et al. Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation. BMC Cancer. 2015 Jan 22:15:17.
警示图
警示词
Warning
危险申明
H302-H315-H319-H335
警告申明
P261-P264-P270-P271-P280-P302+P352-P304+P340-P321-P330-P362+P364-P405-P501
GHS 编码
GHS07
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