最新药物分子砌块-2020/9 2020/9/15 10:05:29

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In the last few years, increasing attention has been paid to the imidazo[1,5-a]pyridine nucleus[1]. The imidazo[1,5-a]pyridines are an important class of heterocyclic compounds owing to their photophysical and biological properties. They have found utility in a number of areas of research including potential applications in organic light-emitting diodes (OLED) and thin-layer field effect transistors (FET). In addition they have been investigated in a wide range of potential pharmaceutical applications, including HIV-protease inhibitors, and Thromboxane A2 synthesis inhibitors[2-6].

A series of medicinal products containing imidazo[1,5-a]pyridine has been firmly incorporated in medical practice.
A series of medicinal products containing imidazo[1,5-a]pyridine has been firmly
incorporated in medical practice.

[1] Dyes and Pigments (2019), 171, 107713.
[2] European Journal of Medicinal Chemistry (2011), 46(6), 2427-2435.
[3] European Journal of Medicinal Chemistry (2015), 103, 289-301.
[4] Bioorganic & Medicinal Chemistry Letters (2005), 15(8), 2129-2134.
[5] Bioorganic & Medicinal Chemistry Letters (2015), 25(15), 2907-2912.
[6] Bioorganic & Medicinal Chemistry Letters (2016), 26(24), 5887-5890.

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